FRIDAY, Sept. four, 2020 (HealthDay News)
Persons with lupus are not at greater chance of hospitalization from COVID-19 thanks to steroidal prescription drugs they choose to lessen immune technique action, a new study finds.
And a relevant study found that people with inflammatory kinds of arthritis — this kind of as rheumatoid arthritis — are not more likely to be hospitalized with COVID-19 than people with out arthritis.
Both of those scientific tests have been led by scientists at NYU Grossman University of Medication, in New York Metropolis.
The conclusions “ought to reassure most patients, specifically people on immunosuppressant therapy, that they are at no higher chance of having to be admitted to clinic from COVID-19 than other lupus or arthritis patients,” Dr. Ruth Fernandez-Ruiz, co-creator of the scientific tests, claimed in an NYU Langone information release.
“Persons with lupus or inflammatory arthritis have the exact chance factors for getting very seriously sick from COVID-19 as people with out these conditions,” claimed Fernandez-Ruiz, a postdoctoral fellow in rheumatology.
Lupus and circumstances like rheumatoid arthritis, psoriatic arthritis and spondyloarthritis are autoimmune disorders in which the immune technique mistakenly assaults a person’s very own tissues. This triggers irritation in the joints, skin, kidneys and other elements of the system.
The scientists found that lupus patients getting immune-suppressing prescription drugs — this kind of as mycophenolate mofetil (CellCept) and azathioprine (Imuran) — experienced no higher chance of hospitalization (15 out of 24) than lupus patients not working with the prescription drugs (9 of seventeen).
In addition, the COVID-19 hospitalization charge for people with inflammatory arthritis (26%) was equivalent to that of New York Metropolis inhabitants all round (25%).
A different obtaining was that patients getting biologic medications for arthritis, this kind of as adalimumab (Humira) and etanercept (Enbrel), or the antiviral hydroxychloroquine, experienced no higher or lessen chance of COVID-19 hospitalization than people not getting the medications.
But patients who took steroids referred to as glucocorticoids, even in mild doses, experienced a ten moments better chance of COVID-19 hospitalization than people who failed to choose steroids. While the obtaining is statistically significant, the study’s compact measurement may overestimate the real chance, the scientists observed.
The scientific tests have been just lately revealed on line in the journal Arthritis and Rheumatology.
— Robert Preidt
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Resource: NYU Langone, information release, Aug. 25, 2020