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COVID-19 Is Far More Lethal, Damaging Than Flu, Data Shows

FRIDAY, Dec. 18, 2020 (HealthDay Information)

COVID-19 is considerably a lot more harmful and lethal than the seasonal flu, new scientific studies validate.

Scientists analyzed U.S. Office of Veterans Affairs facts on a lot more than three,600 clients hospitalized with COVID-19 involving Feb. 1 and June seventeen of this 12 months, and a lot more than 12,600 hospitalized with the flu involving Jan. 1, 2017 and Dec. 31, 2019. The ordinary age of clients in equally groups was 69.

The demise rate among COVID-19 clients was 18.five%, when it was five.three% for these with the flu. These with COVID were being nearly 5 occasions a lot more probable to die than flu clients, in accordance to the analyze posted online Dec. 15 in the BMJ.

COVID-19 clients with the greatest threat of demise integrated these aged seventy five and older who also experienced persistent kidney illness or dementia, and Blacks who were being obese, or who experienced diabetic issues or kidney illness.

The analyze also found that COVID-19 clients were being four occasions a lot more probable to require breathing machines, nearly 2.five occasions a lot more probable to be admitted to intense treatment, and stayed in the hospital an ordinary of a few times longer than flu clients.

A independent analyze from France, posted online Dec. seventeen in The Lancet Respiratory Drugs journal, arrived at related conclusions: Approximately two times as quite a few individuals were being admitted to the hospital for COVID-19 at the peak of the pandemic than were being for influenza at the peak of the 2018/2019 flu time. And the demise rate was practically a few occasions larger.

The French crew, led by Dr. Pascale Tubert-Bitter, investigation director at L’Institut Nationwide de la Santé et de la Recherche Médicale (Inserm), and Catherine Quantin, from the College Healthcare facility of Dijon and Inserm, in contrast facts from COVID-19 clients admitted to the hospital about a two-month time period in spring 2020 with influenza clients admitted about a a few-month time period during the seasonal flu outbreak of 2018/2019.

“The locating that the COVID-19 demise rate was a few occasions larger than for seasonal influenza is especially placing when reminded that the 2018/2019 flu time experienced been the worst in the past 5 several years in France in phrases of selection of fatalities,” Quantin mentioned in a Lancet news launch.

Tubert-Bitter additional, “Taken jointly, our conclusions evidently suggest that COVID-19 is a great deal a lot more significant than seasonal influenza. At a time when no treatment has been revealed to be productive at protecting against extreme illness in COVID-19 clients, this analyze highlights the relevance of all steps of physical avoidance and underlines the relevance of productive vaccines.”

U.S. researchers reported a large shock in their analyze was that COVID-19 clients experienced a larger threat of producing diabetic issues, with nine a lot more circumstances for every 100 than flu clients.

“These clients failed to have diabetic issues until eventually they bought COVID-19,” reported analyze senior creator Dr. Ziyad Al-Aly, an assistant professor of medicine at Washington College in St. Louis. “Then their blood sugar spiked, and they necessary huge doses of insulin. Is the diabetic issues reversible, or will it require long-time period administration? Will it be form 1 or form 2 diabetic issues? We just don’t know due to the fact COVID-19 scarcely existed a 12 months ago.”

An additional locating was that COVID-19 clients experienced a larger threat of acute kidney injury and extreme sepsis shock. For equally issues, there were being an ordinary of 6 a lot more circumstances for every 100 COVID-19 clients than among flu clients.

Also, COVID-19 clients were being a lot more probable to need drugs to treat seriously very low blood tension, a problem that can guide to organ injury and demise. The rate was eleven.five a lot more circumstances for every 100 clients than among flu clients.

“Lots of large-profile, public comparisons involving COVID-19 and the flu have been produced nevertheless, these comparisons primarily were being drawn working with disparate facts and statistical strategies that have resulted in a large amount of conjecture. Our investigation signifies an apples-to-apples comparison involving the two health conditions,” Al-Aly reported in a university news launch.

“A deeper knowledge of the health and fitness risks of COVID-19 assists to foresee need for health and fitness treatment solutions and to venture mortality with increased precision,” he additional.

“We know so little about COVID-19 due to the fact of its newness,” Al-Aly mentioned. “I’m not confident why Black clients undergo and die a lot more. My hunch is that the induce relates to racial disparities in health and fitness treatment, but there could be other elements that we don’t nonetheless know.”

More info

The U.S. Centers for Condition Manage and Avoidance has a lot more on COVID-19.

Sources: Washington College in St. Louis, news launch, Dec. 15, 2020 The Lancet Respiratory Drugs, news launch, Dec. seventeen, 2020

Robert Preidt

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