J & J’s Booster Brings Robust Protection Against Omicron, Study Shows

News Picture: J & J's Booster Brings Robust Protection Against Omicron, Study ShowsBy Ernie Mundell HealthDay Reporter

THURSDAY, Dec. thirty, 2021 (HealthDay Information)

New facts out of South Africa finds that a booster dose of Johnson & Johnson’s COVID-19 vaccine seems to provide solid protection towards extreme condition prompted by the fast-spreading Omicron variant.

The study, which was printed on line and has not nonetheless undergone peer critique, was performed in a team of far more than 69,000 South African well being care workers. All of them bought their boosters six to 9 months just after possessing by now gained a person dose of the J & J vaccine.

The boosted well being workers’ outcomes were as opposed to a comparable selection of unvaccinated South Africans.

The study found that people who’d gotten the J & J booster shot were eighty five% much less most likely to demand hospitalization thanks to an infection from Omicron, as opposed to unvaccinated people.

That compares properly to other facts from South Africa displaying that a booster shot of the two-dose Pfizer vaccine minimize the danger of hospitalization by 70%.

The new facts flies in the facial area of recent recommendations from the U.S. Centers for Condition Regulate and Avoidance. The CDC is continue to authorizing use of the J & J vaccine, but is recommending that other vaccines, this sort of as the Pfizer or Moderna photographs, be favored as boosters. The company primarily based its recommendation on a elevated danger of quite exceptional but probably daily life-threatening blood clots tied to use of the J & J vaccine.

In a separate U.S. arm of a demo that wrapped up in September — when the Delta variant was continue to dominating — Johnson & Johnson found that offering people a second dose of the vaccine two months just after they’d gained their first prompted protection from COVID-connected hospitalization to increase from 74% before the booster to ninety four% just after. Comparable outcomes have been observed in trials across 10 nations.

Even though the massive greater part of vaccinated People have gained either the Pfizer or Moderna mRNA vaccines, populations in Africa and elsewhere have normally relied on the a person-dose Johnson & Johnson shot. So, the new findings could be a real boon to people in producing nations, gurus believe.

The new South African findings on J & J boosters come as relatively of a surprise, since laboratory experiments found the photographs had minimal performance towards the really mutated Omicron variant. Even so, gurus believe the booster may possibly increase levels of antibodies to robust levels, or may perhaps perform on other players in the human immune procedure to enable battle off the variant.

Far more information:

There’s far more on the Omicron variant of the new coronavirus at the CDC.

Resources: medRxiv, on line publication, Dec. 29, 2021

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